• Rosa Salazar as Alita, the titular cyborg heroine. Salazar portrays the role by way of motion capture.
• Christoph Waltz as Dr. Dyson Ido, a scientist who is Alita's caretaker.
• Jennifer Connelly as Dr. Chiren,[14] ex-girlfriend of Ido, who escaped with him from the false utopia of Zalem/Tiphares, but became disenchanted with real freedom.
• Mahershala Ali as Vector, a man who rigs Motorball combat matches.
• Ed Skrein as Zapan, a cyborg tasked with tracking down and killing Alita.
• Jackie Earle Haley as Grewishka, a huge cyborg based on Grewcica from the Battle Angel OVA.
• Keean Johnson as Hugo, Alita's love interest who also teaches her to play a gladiator-style game called Motorball.
• Michelle Rodriguez as Gelda, a cyborg warrior from Mars who trained Alita.
• Eiza González as Nyssiana, a cyborg tasked with tracking down and killing Alita.
• Lana Condor as Koyomi, an orphaned teen and freelance photographer.
• Jorge Lendeborg Jr. as Tanji, a friend of Hugo's.
• Idara Victor as Nurse Gerhad, Ido’s aide.
• Leonard Wu as Kinuba
• Marko Zaror as Ajakutty, a Motorball player.
• Elle LaMont as Screwhead, a cyborg tasked with tracking down and killing Alita.
• Casper Van Dien as Amok

An action-packed story of one young woman's journey to discover the truth of who she is and her fight to change the world. Source:IMDB

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