A lion who is the crown prince of the Pride Lands. Glover said that the film will focus more on Simba's time growing up than the original film did, stating that "[Favreau] was very keen in making sure we saw [Simba's] transition from boy to man and how hard that can be when there's been a deep trauma

A slow-witted common warthog who befriends and adopts a young Simba after he runs away from home. Rogen said, "[a]s an actor, I [...] don't think I'm right for every role — there are a lot of roles I don't think I'm right for even in movies I'm making — but Pumbaa was one I knew I could do well".

The treacherous brother of Mufasa and the uncle of Simba who seeks to take the mantle of king of the Pride Lands. Ejiofor described Scar as more "psychologically possessed" and "brutalized" than in the original film. Ejiofor said that "especially with Scar, whether it's a vocal quality that allows for a certain confidence or a certain aggression, to always know that at the end of it you're playing somebody who has the capacity to turn everything on its head in a split second with outrageous acts of violence – that can completely change the temperature of a scene". Ejiofor also said that "[Scar and Mufasa's] relationship is completely destroyed and brutalized by Scar's way of thinking. He's possessed with this disease of his own ego and his own want". Favreau said of casting Ejiofor, "[He] is just a fantastic actor, who brings us a bit of the mid-Atlantic cadence and a new take on the character. He brings that feeling of a Shakespearean villain to bear because of his background as an actor. It's wonderful when you have somebody as experienced and seasoned as Chiwetel; he just breathes such wonderful life into this character.

The Queen of the Pride Lands, Mufasa's mate, and Simba's mother.

A wise-cracking meerkat who befriends and adopts a young Simba after he runs away from home.

The King of the Pride Lands and the father of Simba. Jones reprises his role from the original 1994 animated film. According to Favreau, Jones' lines remain mostly the same from the original film.Ejiofor said that "the comfort of [Jones reprising his role] is going to be very rewarding in taking [the audience] on this journey again. It's a once-in-a-generation vocal quality". Favreau saw Jones' return as "carrying the legacy across" the original film and the remake, and felt that his voice's change in tonality compared to the original film "served the role well because he sounds like a king who's ruled for a long time"

Simba's childhood best friend and future love interest. According to Favreau, the character has a bigger role than in the original film. Favreau felt that "part of [Beyoncé joining the film] is that she's got young kids, part of it is that it's a story that feels good for this phase of her life and her career, and she really likes the original very much. And then, of course, there are these wonderful musical numbers that she can be involved with, and my God... she really lives up to her reputation as far as the beauty of her voice and talent".

Joseph reprises her role from the Broadway production. Joseph chose to work on the film because "Nala inspires little girls [...] She's a great role model".